Andy Stitzer is an amiable single guy who works at a big-box store; living alone, 40-year-old Andy spends his free time playing video games and curating his action-figure collection; despite his age, Andy has never had sex, so his friends, including the laid-back David, push Andy towards losing his virginity; while attempting to get over his awkwardness around female customers, Andy meets local shop owner Trish and they begin a tentative romance.